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Association of serum selenium with thyroxin in severely iodine-deficient young children from the Amhara region of Ethiopia
Overview
This study investigated the association of serum selenium levels of severely iodine-deficient children (54-60 months) from the Amhara region of Ethiopia.
A cross-sectional study was used to analyze serum selenium, thyroid-stimulating hormone, total thyroxin, total triiodothyronine and thyroglobulin. In addition, iodine in urine and household salt was analyzed, and the presence of goiter was assessed.
Selenium-deficient children were found to have higher levels of the thyroid hormone thyroxin (T4) than children with normal a normal serum selenium concentration. Because selenium influences thyroid metabolism, this evidence may endanger the effectiveness of the salt iodization program.
Publication
European Journal of Clinical Nutrition